Artificial human ear grown in lab

July 31, 2013
By

EarThe ear made from animal tissue bends like a real ear

US scientists say they have moved a step closer to being able to grow a complete human ear from a patient’s cells.

In a new development in tissue engineering, they have grown a human-like ear from animal tissue.

The ear has the flexibility of a real ear, say researchers at Massachusetts General Hospital in Boston.

The technique may one day be used to help people with missing or deformed outer ears, they believe.

Tissue engineering is a growing field in medical science, where substitute organs are made in the laboratory in the hope of using them to replace damaged ones.

Continue reading the main story

Start Quote

This research is a significant step forward in preparing the tissue-engineered ear for human clinical trials”

End Quote
Dr Thomas Cervantes
Massachusetts General Hospital

The US research team is working on artificial living ears to help people born with malformed ears or who have lost them in accidents or trauma.

Previously the researchers had grown an artificial ear, the size of a baby’s, on a mouse.

In the latest development, published in the Journal of the Royal Society Interface, they took living tissues from cows and sheep and grew them on a flexible wire frame that has the 3D shape of a real human ear.

This was then implanted into a rat whose immune system they had suppressed enabling the ear to grow.

“We’ve demonstrated the first full-sized adult human ear on the rat model,” Dr Thomas Cervantes, who led the study, told BBC News.

It was significant for several reasons, he said.

“One – we were able to keep the shape of the ear, after 12 weeks of growth in the rat. And then secondly we were also able to keep the natural flexibility of the cartilage.”

Titanium scaffold

The cells were grown on a titanium wire scaffold that is modelled on the dimensions of a real human ear, taken from CT scans.

The new work shows that in theory it is possible to grow up enough cells – at least in animals – to make a full-size human ear.

“In a clinical model, what we would do is harvest a small sample of cartilage, that the patient has, and then expand that so we could go ahead and do the same process,” said Dr Cervantes.

“This research is a significant step forward in preparing the tissue-engineered ear for human clinical trials.”

He said he expected that the process could move into human clinical trials in about five years.

Other research into bioengineered organs is progressing fast.

About a dozen patients have received transplants of artificial wind pipes coated with stem cells taken from either the patient or a donor.

Meanwhile, a kidney grown in the laboratory has been transplanted into a rat, where it started to produce urine.

Article source: http://www.bbc.co.uk/news/health-23508688#sa-ns_mchannel=rss&ns_source=PublicRSS20-sa The feed :

Tags:

Sponsored By:

The Deeter Group

Deeter Electronics Ltd. | Deeter Electronics Inc | Deeter Group Asia | Deeter Group Germany | Deeter Group Corporate

Head & Registered Office:
Deeter Electronics Ltd.
Deeter House,
Valley Road,
Hughenden Valley,
Bucks. HP14 4LW

Tel: +44 (0) 1494 566 046
Fax: +44 (0) 1494 563 961
E-mail: [email protected]


The Deeter Group with products ranging from: , , , continuous , 4-20mA , , , , , , , a , wireless sensor and much more.

If you want a standard or a custom level switch, float switch, level sensor, or wireless sensor, contact us via email [email protected] or call us now on 01494 566 046.

Company Name: The Deeter Group

Location: Hughenden Valley, UK

Deeter Electronics USA
Deeter Electronics USA
Wireless sensor system | Radio telemetry | Level switches | Level sensors | Liquid level sensor | Float switches | Controllers & indicators | Industrial weighing equipment | Electronic circuit design & manufacture | Software design | Reed relays | Ultrasonic level flow sludge & proximity sensors | Proximity sensors & switches | Reed switches | Litz wire | Wago Terminals | Mechanical & magnetic floats | Boiler control |

Deeter Electronics UK
Wireless sensor system | Radio telemetry | Level switches | Level sensors | Liquid level sensor | Float switches | Controllers & indicators | Industrial weighing equipment | Electronic circuit design & manufacture | Software design | Reed relays | Ultrasonic level flow sludge & proximity sensors | Proximity sensors & switches | Reed switches | Litz wire | Wago Terminals | Mechanical & magnetic floats | Boiler control |

Deeter Electronics Europe
Wireless sensor system | Radio telemetry | Level switches | Level sensors | Liquid level sensor | Float switches | Controllers & indicators | Industrial weighing equipment | Electronic circuit design & manufacture | Software design | Ultrasonic level flow sludge & proximity sensors | Proximity sensors & switches | Reed switches | Litz wire | Wago Terminals | Mechanical & magnetic floats | Boiler control |

Sensor Magazine Websites
Explosion Proof Sensors UK | Explosion Proof Sensors | Water Level Measurement | Liquid Level Sensing | Liquid Level Measurement | Liquid Level Sensors UK | Liquid Level Sensors Europe | Wireless Sensors | Sensor Magazine | Industrial Sensors



Water use